James has patent prosecution experience in Australia and New Zealand, as well as in assisting in the management of large patent portfolios, especially in South Asia. His diverse postdoctoral work at Monash University included total synthesis of the tricyclic marine alkaloids (-)-lepadiformine and (-)-fasicularin, and the design and synthesis of novel peptide analogues which have potential for use as non-opioid analgesics. He was also involved in the production and examination of several organometallic complexes for olefin metathesis to be used in production of functionalised nylon monomers.
He completed his PhD at the University of Nottingham, focusing on the biomimetic synthesis of natural products. Alongside this work, he also developed methodology for the synthesis of amide bonds, aryne functionalization and azide reduction. Furthermore he aided in authoring a book chapter concerning the application of electrocyclization reactions in natural product synthesis and was the recipient of a prestigious Royal Society of Chemistry scholarship.
While completing his MSci he undertook projects at both AstraZeneca and Pfizer working on antileukemic compounds of interest and flow technology respectively. James has published many articles in internationally recognised journals.